Going into the Combine, we know:
* CJ Henderson and Darnay Holmes are super fast
* Okudah and Jaylon Johnson are elite athletes, who I'd guess will run under 4.45.
Gladney looks very fast and explosive, and I see that many expect him to run in the 4.3's.
I understood people worrying about Jamel Dean's injury history, but I didn't get the rest of their reservations. As an athlete, he was very similar to the CB version of DK Metcalf - except Dean has average agility instead of terrible agility. He played really well at Auburn, but people worried about his overly-physical style of coverage translating. Excuse me, but if I have a 6'2, 206 lb CB, who runs a 4.3 40 and jumps 41 and 130", and my big concern is him playing too physical, I'm taking him in the 1st Round. He was outstanding in a part-time role in 2019, and many analysts and fans wondered why he wasn't a fulltime player. His injuries did concern me enough to knock him out of the Top 40, but if he stays healthy he's the goods.
The point is just that I wouldn't get caught up in nitpicking CB play. If a guy is good and an elite athlete, you should take him over the guy that's a better college player but just a good or OK athlete. If a guy is good enough to be considered in the 1st Round, and he runs fast and tests well in general, that pick is likely to hit (you can find a post where I go into greater detail somewhere in the Draft Forum, but I looked into it, and 1st RD CB's who run 4.45 or better and test elite overall represent a ton of hits and very few misses).