Theres so many reasons you cant use a wishbone in the NFL its too long to list them all. Here's a few:
1. The wishbone is east-west offense; defenses want teams to run east west cause that means theyre going nowhere in terms of gaining yards.
2. Defenses are simply too fast to do it. Look @ miami for the last few years; anything on the edges on a run play was, with rare exceptions, going nowhere for our opposition.
3. Your qb takes too many hits running the ball and waiting for the right time to toss it.
4. If it gets sniffed out its going to lead to a lot of fumbles and negative plays. 2 major no no's.