There definitely is the opportunity to run a power scheme now because, as SoS said, nearly everyone in the NFL runs some variety of the ZBS. That's what Harbaugh was doing in San Francisco to so much success, running power schemes against defenses designed for zone schemes. He added a fullback and often used extra OL as "TE's" to bulldoze those undersized LB's and DT's, and then by the 4th quarter they were so worn out from the physicality of it all, that the defenses just wilted.
As they overcompensated by putting more men in the box, that opened them up for the deep shots down field. That's precisely why Harbaugh wanted Kaepernick, because he had an absolute cannon for an arm and plenty of willingness to fling it downfield against that 1v1 coverage. If it broke down, he was a big strong runner who could salvage the play by running for yards. Alex Smith was reticent to throw deep, so Harbaugh got impatient and replaced him, just so he could facilitate his running game with the threat of the deep pass to keep the safeties honest.
It worked, look at the LB's these days, most are garbage. Why? Because they're being asked to do so many things it's nearly impossible to be good at all of them. Whatever your weakness, the offense will isolate and exploit the mismatch. Today guys like Ryan Shazier are all the rage ... basically fast safeties playing LB, because they have the speed to blitz and cover. Most offenses use the short pass as their bread and butter today, so a LB who can't cover (like ours!) is going to be exploited a lot ... and I mean a LOT. But, those guys fast and quick enough to cover slot receivers and big enough to cover TE's are rare. Those guys tend to be used as pass rushers if they're over 6'2 and coverage DB's if they're under 6'2. Those great athletes aren't being funneled to LB anymore, because no matter how good they are, they're going to be exploited by something.
But almost all of the OL's either run a full ZBS scheme or some kind or a mixture of both zone and power concepts with a heavy emphasis on zone. Defenses have been losing to it, so all of the NFL has migrated to it. Remember when Shanahan used to make every RB look like a HoF'er? That was because of those zone schemes. It worked so well, everyone adopted it. Just like everyone adopted the West Coast Offense or at least heavily incorporated it's concepts into their offenses. The ZBS is a perfect fit for the West Coast Offense systems.
Boone represents a power guy in a time when there aren't many power schemes being run. While he's not the player he used to be, he's also not surrounded by other dominating power guys who block out the sun and wear down the defense. Still, I'd like to see what he's got left in the tank. We're not looking for the old Boone, we couldn't afford him. But we are looking for a serviceable OL.