Yeesh. Animal research sounds cruel (whether mice, dogs, rabbits, guinea pigs, rats, snakes, pigs), but is unfortunately absolutely essential to medical progress in this day and age. Period. Can it be done more ethically? Sure. Can it be further streamlined to minimize waste and unnecessary suffering for these animals? Yes. And the people who write protocols for these kinds of studies have to jump through A LOT of hoops to prove their studies are worthwhile and minimize the harm and waste involved. And if there is another way to ask and answer the research question being addressed by the animal studies, it is always preferred. Nobody likes harming the animals, even researchers who use animals.
I'm curious how many of you dog (or insert your favorite animal here) lovers would sign up to be the guinea pigs for new drugs or treatments instead of the animals? Should we just start testing on humans from ground zero? Hey, I've got a new drug for disease X that seems to work in a petri dish. I can just start giving it to patients, right? Or, I want to better understand disease X. Can I just kill a few disease X patients so I can harvest their cells and organs? How could medicines and treatments be developed and tested before they are administered to your mom? Your son?
At some point in the process of understanding a disease or developing a treatment, you need a MODEL of that disease. And if you look at the diseases we REALLY don't have a f-ing clue about, it's the ones that we can't or don't know how to model in animals. We'd be a lot closer to understanding autism if we had a legit mouse/dog/monkey model of autism. I'm sure anyone with familiarity with autism as well as animals can understand why modeling it might be challenging...
The fact that there exists an animal model of MD, whether dog or other animal, bodes well for the future of patients with that affliction.
I'm all for respecting animals and not harming them in any way, but I don't think people realize without animal research - which is truly the foundation of most meaningful medical research today - you'd be giving up the progress of the last several decades. I am surprised that Ryan Tannehill, touted on this forum as some kind of pre-med wunderkind, fails to grasp this. But it's easy to feel this way if you like animals and don't know a damn thing about medicine or science. Animal research SHOULD cause any reasonable human being some discomfort, and as a society we should strive to make it as humane as possible, so that these animals do not live and die in vain. But the benefits far, far outweigh the downsides.
NOTE: I'm speaking about federally-funded animal research, which is completely different from the oft-cited examples of cosmetics or other frivolous products being tested on bunnies, etc.