The Dolphins are the better team. They are also likely to be quite angry/embarrassed about losing to the Jets, and they will take it out on the Saints.
Jay Cutler is a fairly good fit for the Miami offense, and he has a top runner in Jay Ajayi who can make big plays. Wide receivers Kenny Stills and DeVante Parker are capable of coming up with key catches against a generous New Orleans secondary.
The Saints should be able to move the ball fairly well with
Drew Brees under center and a top-flight wide receiver in Michael Thomas, but they are going to be in the chase mode throughout the game, and the Dolphins will remain in control.
Look for the Dolphins to earn the victory here.
New Orleans at Miami, NO -2.5, Miami 28, New Orleans 21