The Cards will be fine. They always seem to find a way to overcome these things, as they've dealt with injuries to one of their stars every single year.
The Cards will win the Central (again) and the people who are thinking this is going to become a race soon, haven't seen how the other teams involved are playing. They're going to actually have to start winning games to have a shot. The Astro's are way back, while everyone will cite the fact that they were so far under .500 last year and the year before, they forget that was just for the WC, they finished double digit games back.
The Reds I hope no one really considers for real, they just don't have the arms to stay in it, especially since they have to throw Harang and Arroyo until their arms about fall off each time they start.