It's an interesting point. I think the WR's will have to adjust to perfectly placed throws.
The direction the ball spins makes no difference at all. I know it's just HS, but my my freshman and sophomore year we had a right handed QB, and my Jr. And Sr. Year we had a lefty. It made no difference whatsoever(when the ball was thrown accurately).
Dammit you beat me to it!get some Australian WRs. they are used to the spiral running the other way