Personally, Latu's injury doesn't worry me. It's not an injury you see people re-injure once they recover. You see some people never fully recover, but once they do it tends not to be an issue. And Latu has played with it for two seasons w/o issue.
The injury that would worry me Newton's. I had him as a pick I would have been fine with at 21. In fact, I thought he would have been a bargain there as I see him as having top 10 talent. However that Jones fracture is concerning. That's an injury you see players re-injure repeatedly.