Nonsense.
I respect your opinion, here's mine.
Difference is going to be more of an advantage to the Dline than anywhere else because they are close enough to hear it consistently.
Dline can hear the cadence and pin their ears back when they know its a pass play to get the sack, play more cautious and alert for the RB when they know its a running play. The Oline sucked this year due to talent, I know, but IMHO the cadence did not help them and was one of the reasons we broke the Franchise record for sacks allowed.
If you personally do not have the timing nor the ability to get a jump on someone, even if its just a millisecond of an advantage, when they are basically telegraphing what they will do to you, well then, sad to hear it.