Most people would agree that the most important units on the team are Oline and Dline, yes? Therefore, I would argue that drafting one of those is precisely the definition of a "difference maker". You're supposed to build your team from the inside out so I completely disagree with the notion that you should skimp on lineman because you "could find good right tackles on day 2 regularly". You're essentially saying an offensive lineman is less important than a linebacker or a #2 corner.
You'd rather have a DE than RT? I'm fine with that, but let's not pretend like RTs are somewhere in the bottom half of important positions here.
Also for the people who aren't really thinking about a possible tanking effort, you might also want to factor in that if the eventual goal is Tua, who is left handed, that RT should be just as important as finding a franchise LT.